Single Molecule AFM Force Spectroscopy Analysis of Alpha-Synuclein Misfolding
نویسندگان
چکیده
منابع مشابه
Statistical Analysis of Single-Molecule AFM Force Spectroscopy Curves
We develop a statistical framework for the quantitative characterization and analysis of force-extension curves obtained from single-molecule force spectroscopy (SMFS) measurements. We apply this methodology to force-extension data obtained for elastinlike polypeptides (ELPs) with precisely engineered molecular architectures, where we demonstrate that our approach enables SMFS to be used to stu...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.11.2163